Activity record

PGDB_A005207

Assay: viabilityTarget: VAV1QC: ambiguous
Activity overview

IC50 = 0.039 nM

TargetVAV1
Cell linepan-T
Assay / Readoutflow_cytometry / IC50
Assay IDPGDB_AS000112
PatentWO2026051943A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C029516
Compound IDPGDB_C029516
Compound实施例157
Source record IDPGDB_C029516
InChIKeyXEGRMHMTZVKOBU-UCFFOFKASA-N

Assay context

Assay IDPGDB_AS000112
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyflow_cytometry
TargetVAV1
E3Not specified
Cell linepan-T
OrganismHomo sapiens

Source evidence

Patent IDWO2026051943A1
Compound location

实施例157

实施例157 enlarged structure实施例157 location on patent page 162
Activity table
Page 261 · table start
Page 262 · table middle
Page 263 · table end