Activity record

PGDB_A007660

Assay: % DegradationTarget: IKZF1QC: ambiguous
Activity overview

degradation = 24 %

TargetIKZF1
Concentration1 uM
Assay / Readout% Degradation
Assay IDPGDB_AS000768
PatentWO2024059107A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002831
Compound IDPGDB_C002831
Compound80;80;80
Source record IDPGDB_C002831
InChIKeyVUGINFJQDOWAIE-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000768
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Concentration1 uM
Detection targetprotein_degradation
TargetIKZF1
E3Not specified

Source evidence

Patent IDWO2024059107A1
Compound location

80;80;80

80;80;80 enlarged structure80;80;80 location on patent page 11
Activity table
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