Assay

PGDB_AS000768

System: cell_basedTarget: IKZF1
Assay context summary

Assay context

43 activity records
Assay family% Degradation
Systemcell_based
Readout% Degradation
TargetIKZF1
E3Not specified
Detection targetprotein_degradation
Activity compounds and values

Activity records

43 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C002831
% Degradation-=24%1 uM-IKZF1--WO2024059107A1PGDB_A007660PGDB_C002831PGDB_AS000768View
2D structure for PGDB_C002828
% Degradation-=7%1 uM-IKZF1--WO2024059107A1PGDB_A008146PGDB_C002828PGDB_AS000768View
2D structure for PGDB_C002812
% Degradation-=84%1 uM-IKZF1--WO2024059107A1PGDB_A010621PGDB_C002812PGDB_AS000768View
2D structure for PGDB_C002817
% Degradation-=35.2%1 uM-IKZF1--WO2024059107A1PGDB_A015293PGDB_C002817PGDB_AS000768View
2D structure for PGDB_C002821
% Degradation-=98.4%1 uM-IKZF1--WO2024059107A1PGDB_A016965PGDB_C002821PGDB_AS000768View
2D structure for PGDB_C002808
% Degradation-=98.1%1 uM-IKZF1--WO2024059107A1PGDB_A017058PGDB_C002808PGDB_AS000768View
2D structure for PGDB_C002835
% Degradation-=32.5%1 uM-IKZF1--WO2024059107A1PGDB_A019541PGDB_C002835PGDB_AS000768View
2D structure for PGDB_C002829
% Degradation-=17.2%1 uM-IKZF1--WO2024059107A1PGDB_A019660PGDB_C002829PGDB_AS000768View
2D structure for PGDB_C002841
% Degradation-=6.3%1 uM-IKZF1--WO2024059107A1PGDB_A024767PGDB_C002841PGDB_AS000768View
2D structure for PGDB_C002846
% Degradation-=9.1%1 uM-IKZF1--WO2024059107A1PGDB_A024840PGDB_C002846PGDB_AS000768View
2D structure for PGDB_C002826
% Degradation-=98.6%1 uM-IKZF1--WO2024059107A1PGDB_A030096PGDB_C002826PGDB_AS000768View
2D structure for PGDB_C002848
% Degradation-=4.1%1 uM-IKZF1--WO2024059107A1PGDB_A030113PGDB_C002848PGDB_AS000768View
2D structure for PGDB_C002813
% Degradation-=8.8%1 uM-IKZF1--WO2024059107A1PGDB_A031405PGDB_C002813PGDB_AS000768View
2D structure for PGDB_C002815
% Degradation-=27.2%1 uM-IKZF1--WO2024059107A1PGDB_A031495PGDB_C002815PGDB_AS000768View
2D structure for PGDB_C002843
% Degradation-=8.3%1 uM-IKZF1--WO2024059107A1PGDB_A033290PGDB_C002843PGDB_AS000768View
2D structure for PGDB_C002823
% Degradation-=98.4%1 uM-IKZF1--WO2024059107A1PGDB_A033875PGDB_C002823PGDB_AS000768View
2D structure for PGDB_C002811
% Degradation-=9.6%1 uM-IKZF1--WO2024059107A1PGDB_A034276PGDB_C002811PGDB_AS000768View
2D structure for PGDB_C002825
% Degradation-=92.5%1 uM-IKZF1--WO2024059107A1PGDB_A034322PGDB_C002825PGDB_AS000768View
2D structure for PGDB_C002827
% Degradation-=16.2%1 uM-IKZF1--WO2024059107A1PGDB_A037091PGDB_C002827PGDB_AS000768View
2D structure for PGDB_C002822
% Degradation-=97.6%1 uM-IKZF1--WO2024059107A1PGDB_A037673PGDB_C002822PGDB_AS000768View
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