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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A009541

Assay: % DegradationTarget: BRAFQC: standardized

Activity overview

Emax = 9.8 %

TargetBRAF

Cell lineA375.10

Concentration10 uM

Time24 h

Assay / Readoutluminescence / Emax

Assay IDPGDB_AS001074

PatentAU2022290851A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C005759

CompoundExample 107

Source record IDPGDB_C005759

InChIKeyAVMZKTISAAMUBV-KDXMTYKHSA-N

Assay context

Assay IDPGDB_AS001074

Assay family% Degradation

Assay systemcell_based

ReadoutEmax

Technologyluminescence

Concentration10 uM

Treatment time24 h

TargetBRAF

E3Not specified

Cell lineA375.10

Source evidence

Patent IDAU2022290851A1

Compound location

Example 107

Example 107 enlarged structure

Example 107 location on patent page 536

Activity table

Page 229 · table start

Page 230 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU