Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C005759
2 activity records1 related patents
2D structure
N#Cc1c(NS(=O)(=O)N2CCCC2)ccc(F)c1Oc1ccc2ncn(-c3cnc(N4CCN(C(=O)CN5CCC(c6ccc(N[C@H]7CCC(=O)NC7=O)cc6F)CC5)CC4)nc3)c(=O)c2c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Emax | - | = | 9.8 | % | 10 uM | 24 h | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A009541 | PGDB_C005759 | PGDB_AS001074 | View |
| DC50 | - | = | 12.93 | nM | - | — | BRAF | - | A375.10 | AU2022290851A1 | PGDB_A042902 | PGDB_C005759 | PGDB_AS001629 | View |