Activity record

PGDB_A010115

Assay: % DegradationTarget: CDK2QC: standardized
Activity overview

Dmax = 37 %

TargetCDK2
Cell lineHEK293
Concentration10 uM
Time6 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS000735
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008021
Compound IDPGDB_C008021
Compound40;40;40
Source record IDPGDB_C008021
InChIKeyHRDVJHVSETYYBC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000735
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Concentration10 uM
Treatment time6 h
TargetCDK2
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

40;40;40

40;40;40 enlarged structure40;40;40 location on patent page 38
Activity table
Page 528 · table start
Page 529 · table end