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Compound
PGDB_C008021
5 activity records1 related patents
2D structure
O=C1CCC(N2Cc3ccc(CNC(=O)OC4CC(c5ccccc5Cl)C4)cc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 37 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A010115 | PGDB_C008021 | PGDB_AS000735 | View |
| Dmax | - | = | 50 | % | 10 uM | 18 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A027759 | PGDB_C008021 | PGDB_AS002240 | View |
| IC50 | - | = | 0.054 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A042150 | PGDB_C008021 | PGDB_AS002405 | View |
| IC50 | - | = | 0.016 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A044347 | PGDB_C008021 | PGDB_AS000958 | View |
| IC50 | - | = | 0.037 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A045848 | PGDB_C008021 | PGDB_AS000366 | View |