Activity record

PGDB_A010767

Assay: bindingTarget: CRBNQC: ambiguous
Activity overview

Kd = 7.3 nM

TargetCRBN
E3 ligaseCRBN
Cell lineHEK293
Time1 h
Assay / ReadoutKd / binding
Assay IDPGDB_AS001216
PatentIL323841A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008152
Compound IDPGDB_C008152
Compound8
Source record IDPGDB_C008152
InChIKeyNIOPCUUZNLJBKC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001216
Assay familybinding
Assay systemcell_based
ReadoutKd
Treatment time1 h
TargetCRBN | DDB1
E3CRBN | DDB1
Cell lineHEK293

Source evidence

Patent IDIL323841A
Compound location

8

8 enlarged structure8 location on patent page 48
Activity table
Page 58 · table single