Activity record

PGDB_A012580

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

degradation = 93 %

TargetGSPT1
Cell lineHL-60
Concentration10 nM
Time24 h
Assay / ReadoutWestern_blot / percent_remaining
Assay IDPGDB_AS000871
PatentWO2023116835A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000639
Compound IDPGDB_C000639
CompoundA105;A105;A105
Source record IDPGDB_C000639
InChIKeyAFKRNCBQAPFJJP-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000871
Assay family% Degradation
Assay systemcell_based
Readoutpercent_remaining
TechnologyWestern_blot
Concentration10 nM
Treatment time24 h
TargetGSPT1
E3Not specified
Cell lineHL-60

Source evidence

Patent IDWO2023116835A1
Compound location

A105;A105;A105

A105;A105;A105 enlarged structureA105;A105;A105 location on patent page 51
Activity table
Page 141 · table single