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Compound
PGDB_C000639
6 activity records2 related patents
2D structure
CC(NCc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O)C1CCN(c2ncc(-c3cccc(Cl)c3)cc2F)CC1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | = | 93 | % | 10 nM | 24 h | GSPT1 | - | HL-60 | WO2023116835A1 | PGDB_A012580 | PGDB_C000639 | PGDB_AS000871 | View |
| IC50 | - | = | 55 | nM | - | — | - | - | HL-60 | CN117982498A | PGDB_A015184 | PGDB_C000639 | PGDB_AS001350 | View |
| % Degradation | - | = | 93 | % | 10 nM | 24 h | - | - | HL-60 | CN117982498A | PGDB_A027887 | PGDB_C000639 | PGDB_AS001212 | View |
| IC50 | - | = | 55 | nM | - | — | - | - | HL-60 | WO2023116835A1 | PGDB_A033321 | PGDB_C000639 | PGDB_AS000718 | View |
| % Degradation | - | = | -233 | % | 10 nM | 24 h | MYC | - | HL-60 | WO2023116835A1 | PGDB_A043520 | PGDB_C000639 | PGDB_AS002563 | View |
| % Degradation | - | = | -233 | % | 10 nM | - | - | - | HL-60 | CN117982498A | PGDB_A044147 | PGDB_C000639 | PGDB_AS001270 | View |