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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A013562

Assay: % DegradationTarget: IKZF2QC: ambiguous

Activity overview

degradation = 74.8 %

TargetIKZF2

E3 ligaseCRBN

Cell lineHEK293T

Concentration1 uM

Time24 h

Assay / Readout% Degradation

Assay IDPGDB_AS002458

PatentCN117836288A

QC statusambiguous

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C000414

Compound66;66

Source record IDPGDB_C000414

InChIKeyRIQVFCDNSXZUJO-LIMDNCRJSA-N

Assay context

Assay IDPGDB_AS002458

Assay family% Degradation

Assay systemcell_based

Readout% Degradation

Concentration1 uM

Treatment time24 h

Detection targetprotein_degradation

TargetIKZF2

E3CRBN

Cell lineHEK293T

Source evidence

Patent IDCN117836288A

Compound location

66;66

66;66 enlarged structure

66;66 location on patent page 47

Activity table

Page 160 · table start

Page 161 · table middle

Page 162 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU