Activity record

PGDB_A014068

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 1.12 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000095
PatentWO2024032689A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002766
Compound IDPGDB_C002766
CompoundGT-05459
Source record IDPGDB_C002766
InChIKeyPLIXUQPQLRQZRL-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000095
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2024032689A1
Compound location

GT-05459

GT-05459 enlarged structureGT-05459 location on patent page 91
Activity table
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