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Compound
PGDB_C002766
4 activity records1 related patents
2D structure
CC1(C)CCC(CN2CC3CCC(C2)N3Cc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3)=C(c2ccc(Cl)cc2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Degradation | - | > | 50 | % | Concentration context: 500 nM | 24 h | GSPT1 | - | - | WO2024032689A1 | PGDB_A009446 | PGDB_C002766 | PGDB_AS000668 | View |
| IC50 | - | = | 1.12 | uM | - | — | CRBN | CRBN | - | WO2024032689A1 | PGDB_A014068 | PGDB_C002766 | PGDB_AS000095 | View |
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | IKZF3 | - | - | WO2024032689A1 | PGDB_A030299 | PGDB_C002766 | PGDB_AS000176 | View |
| % Degradation | - | < | 50 | % | Concentration context: 500 nM | 24 h | IKZF1 | - | - | WO2024032689A1 | PGDB_A071007 | PGDB_C002766 | PGDB_AS002239 | View |