Activity record

PGDB_A015734

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

EC50 = 87.1 nM

TargetGSPT1
Cell lineHEK293
Time72 h
Assay / Readoutluminescence / EC50
Assay IDPGDB_AS002492
PatentIL323841A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008154
Compound IDPGDB_C008154
Compound16
Source record IDPGDB_C008154
InChIKeyVRESQKVCGUCRSG-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002492
Assay family% Degradation
Assay systemcell_based
ReadoutEC50
Technologyluminescence
Treatment time72 h
TargetGSPT1
E3Not specified
Cell lineHEK293
OrganismHomo sapiens

Source evidence

Patent IDIL323841A
Compound location

16

16 enlarged structure16 location on patent page 54
Activity table
Page 59 · table start
Page 60 · table end