Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C008154
6 activity records1 related patents
2D structure
Cc1cccc(S(=O)(=O)Nc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3=O)c1CCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EC50 | - | = | 87.1 | nM | - | — | GSPT1 | - | HEK293 | IL323841A | PGDB_A015734 | PGDB_C008154 | PGDB_AS002492 | View |
| DC50 | - | > | 10000 | nM | - | — | GSPT1 | - | HEK293 | IL323841A | PGDB_A017290 | PGDB_C008154 | PGDB_AS000381 | View |
| IC50 | - | = | 329.5 | nM | - | — | GSPT1 | - | NCI-H1155 | IL323841A | PGDB_A022664 | PGDB_C008154 | PGDB_AS002011 | View |
| Dmax | - | = | 28.1 | % | Concentration series: 1 nM, 3 nM, 10 nM, 30 nM, 100 nM, 1 uM, 3 uM, 10 uM | 72 h | GSPT1 | - | HEK293 | IL323841A | PGDB_A046975 | PGDB_C008154 | PGDB_AS002464 | View |
| IC50 | - | = | 148 | nM | - | — | GSPT1 | - | NCI-H1155 | IL323841A | PGDB_A052138 | PGDB_C008154 | PGDB_AS000925 | View |
| Kd | - | = | 8.6 | nM | - | — | CRBN | CRBN | HEK293 | IL323841A | PGDB_A061475 | PGDB_C008154 | PGDB_AS001216 | View |