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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A016011

Assay: % DegradationQC: standardized

Activity overview

Emax > 60 %

Cell line293T.114

TimeDC50 > 10000 nM | > 100 nM | DC50 < 100 nM

Assay / Readoutluminescence / Emax

Assay IDPGDB_AS000287

PatentWO2022081927A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C019149

Compound{4494}

Source record IDPGDB_C026792

InChIKeyFZGWYLGHEIXACQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000287

Assay family% Degradation

Assay systemcell_based

ReadoutEmax

Technologyluminescence

Treatment timeDC50 > 10000 nM | > 100 nM | DC50 < 100 nM

TargetGSPT1

E3Not specified

Cell line293T.114

OrganismHomo sapiens

Source evidence

Patent IDWO2022081927A1

Activity table

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A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU