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CN(c1ccc2c3c(cccc13)N(C1CCC(=O)NC1=O)C2=O)C1CCN(Cc2ccccc2)C1| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Emax | - | > | 60 | % | - | DC50 > 10000 nM | > 100 nM | DC50 < 100 nM | - | - | 293T.114 | WO2022081927A1 | PGDB_A016011 | PGDB_C019149 | PGDB_AS000287 | View | |
| DC50 | - | > | 10000 | nM | - | — | GSPT1 | - | 293T.114 | AU2021361043A9 | PGDB_A028131 | PGDB_C019149 | PGDB_AS002445 | View | |
| DC50 | - | > | 100 | nM | - | — | - | - | 293T.114 | WO2022081927A1 | PGDB_A050284 | PGDB_C019149 | PGDB_AS001223 | View | |
| Emax | - | = | 60-95 | % | 10 uM | DC50 > 10000 nM | GSPT1 | - | 293T.114 | AU2021361043A9 | PGDB_A063280 | PGDB_C019149 | PGDB_AS000916 | View |