Activity record

PGDB_A017287

Assay: bindingTarget: CRBNQC: ambiguous
Activity overview

IC50 = 0.15 uM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutIC50 / binding
Assay IDPGDB_AS001908
PatentWO2025043225
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007945
Compound IDPGDB_C007945
Compound14;14;14
Source record IDPGDB_C007945
InChIKeyQEOQIRPMQYGKPV-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001908
Assay familybinding
Assay systembiochemical
ReadoutIC50
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2025043225
Compound location

14;14;14

14;14;14 enlarged structure14;14;14 location on patent page 23
Activity table
Page 525 · table start
Page 526 · table end