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Compound
PGDB_C007945
5 activity records1 related patents
2D structure
Cc1nc(COC(=O)NCc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3)sc1CCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 0.45 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A014045 | PGDB_C007945 | PGDB_AS002528 | View |
| IC50 | - | = | 0.15 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A017287 | PGDB_C007945 | PGDB_AS001908 | View |
| IC50 | - | = | 0.17 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A020055 | PGDB_C007945 | PGDB_AS002309 | View |
| Dmax | - | = | 27 | % | 10 uM | 18 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A020423 | PGDB_C007945 | PGDB_AS001468 | View |
| Dmax | - | = | 30 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A047188 | PGDB_C007945 | PGDB_AS002435 | View |