Activity record

PGDB_A018813

Assay: % DegradationTarget: CDK2QC: standardized
Activity overview

Dmax = 58 %

TargetCDK2
Cell lineHEK293
Concentration10 uM
Time6 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS000677
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007986
Compound IDPGDB_C007986
Compound81;81
Source record IDPGDB_C007986
InChIKeyHIGZQVVGCJQRAU-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000677
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Concentration10 uM
Treatment time6 h
TargetCDK2
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

81;81

81;81 enlarged structure81;81 location on patent page 25
Activity table
Page 527 · table start
Page 528 · table end