Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C007986
5 activity records1 related patents
2D structure
O=C1CCC(N2Cc3ccc(CNC(=O)OCc4cc5n(n4)CC(F)(F)CC5)c(F)c3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 58 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A018813 | PGDB_C007986 | PGDB_AS000677 | View |
| Kd | - | = | 0.35 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A039105 | PGDB_C007986 | PGDB_AS000368 | View |
| IC50 | - | = | 10 | uM | - | — | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A046283 | PGDB_C007986 | PGDB_AS002511 | View |
| Dmax | - | = | 2.7 | % | 10 uM | 6 h | GSPT1 | - | HEK293 | WO2025043225 | PGDB_A058775 | PGDB_C007986 | PGDB_AS000429 | View |
| IC50 | - | = | 0.13 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A065644 | PGDB_C007986 | PGDB_AS001302 | View |