Activity record

PGDB_A020423

Assay: % DegradationTarget: CDK2QC: ambiguous
Activity overview

Dmax = 27 %

TargetCDK2
Cell lineHEK293
Concentration10 uM
Time18 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS001468
PatentWO2025043225
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007945
Compound IDPGDB_C007945
Compound14;14;14
Source record IDPGDB_C007945
InChIKeyQEOQIRPMQYGKPV-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001468
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Concentration10 uM
Treatment time18 h
TargetCDK2
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

14;14;14

14;14;14 enlarged structure14;14;14 location on patent page 23
Activity table
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