Activity record

PGDB_A021741

Assay: % DegradationTarget: CDK2QC: standardized
Activity overview

Dmax = 76 %

TargetCDK2
Cell lineHEK293
Concentration10 uM
Time6 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS000677
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008016
Compound IDPGDB_C008016
Compound112;112;112
Source record IDPGDB_C008016
InChIKeySMUZMEGMGHFGNO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000677
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Concentration10 uM
Treatment time6 h
TargetCDK2
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

112;112;112

112;112;112 enlarged structure112;112;112 location on patent page 27
Activity table
Page 527 · table start
Page 528 · table end