Activity record

PGDB_A022949

Assay: % DegradationTarget: NEK7QC: ambiguous
Activity overview

Dmax > 75 %

TargetNEK7
E3 ligaseCRBN
Assay / ReadoutDmax / % Degradation
Assay IDPGDB_AS002165
PatentWO2025024521A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020365
Compound IDPGDB_C020365
Compound192;Example 192
Source record IDPGDB_C016495
InChIKeyQNNGFOKAAJMETQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002165
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
TargetNEK7
E3CRBN

Source evidence

Patent IDWO2025024521A1
Compound location

192;Example 192

192;Example 192 enlarged structure192;Example 192 location on patent page 84
Activity table
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Page 417 · table middle
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