Activity record

PGDB_A025129

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

degradation = 21.3 %

TargetGSPT1
Concentration1 uM
Assay / Readout% Degradation
Assay IDPGDB_AS001974
PatentWO2024059107A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002829
Compound IDPGDB_C002829
Compound76;76
Source record IDPGDB_C002829
InChIKeyCUVDVAHHZNRMJJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001974
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Concentration1 uM
Detection targetprotein_degradation
TargetGSPT1
E3Not specified

Source evidence

Patent IDWO2024059107A1
Compound location

76;76

76;76 enlarged structure76;76 location on patent page 94
Activity table
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