Activity record

PGDB_A025676

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 4.3 nM

TargetGSPT1
Cell lineSK-BR-3
Time6 d
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS000272
PatentWO2025146129A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C003357
Compound IDPGDB_C003357
Compound25;25
Source record IDPGDB_C003357
InChIKeyJBTZKACAPPAKFY-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000272
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time6 d
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineSK-BR-3

Source evidence

Patent IDWO2025146129A1
Compound location

25;25

25;25 enlarged structure25;25 location on patent page 15
Activity table
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Page 57 · table end