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Compound
PGDB_C003357
3 activity records1 related patents
2D structure
CN(CCOCCc1ccc(NC(=O)Cc2ccc3c(c2F)CN(C2CCC(=O)NC2=O)C3=O)cc1Cl)C(=O)COCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 4.3 | nM | - | — | GSPT1 | - | SK-BR-3 | WO2025146129A1 | PGDB_A025676 | PGDB_C003357 | PGDB_AS000272 | View |
| Dmax | - | = | 125 | % | 5 mM | 4 h | GSPT1 | - | NB4 | WO2025146129A1 | PGDB_A028740 | PGDB_C003357 | PGDB_AS000646 | View |
| DC50 | - | = | 3.6 | nM | - | — | GSPT1 | - | NB4 | WO2025146129A1 | PGDB_A068007 | PGDB_C003357 | PGDB_AS002359 | View |