Assay

PGDB_AS000272

System: cell_basedCell line: SK-BR-3
Assay context summary

Assay context

20 activity records
Assay familyviability
Systemcell_based
ReadoutIC50
E3Not specified
Cell lineSK-BR-3
Technologyluminescence
Detection targetcell_proliferation
Activity compounds and values

Activity records

20 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C003344
IC50-=403nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A008002PGDB_C003344PGDB_AS000272View
2D structure for PGDB_C003351
IC50-=209nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A017357PGDB_C003351PGDB_AS000272View
2D structure for PGDB_C003349
IC50-=8.6nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A018192PGDB_C003349PGDB_AS000272View
2D structure for PGDB_C003338
IC50-=16nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A021306PGDB_C003338PGDB_AS000272View
2D structure for PGDB_C003337
IC50-=86nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A024874PGDB_C003337PGDB_AS000272View
2D structure for PGDB_C003357
IC50-=4.3nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A025676PGDB_C003357PGDB_AS000272View
2D structure for PGDB_C003347
IC50-=470nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A029415PGDB_C003347PGDB_AS000272View
2D structure for PGDB_C003340
IC50-=391nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A031299PGDB_C003340PGDB_AS000272View
2D structure for PGDB_C003353
IC50-=3.1nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A032383PGDB_C003353PGDB_AS000272View
2D structure for PGDB_C003356
IC50-=138nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A037474PGDB_C003356PGDB_AS000272View
2D structure for PGDB_C003339
IC50-=177nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A055177PGDB_C003339PGDB_AS000272View
2D structure for PGDB_C003352
IC50-=9.4nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A061319PGDB_C003352PGDB_AS000272View
2D structure for PGDB_C003350
IC50-=4.6nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A062892PGDB_C003350PGDB_AS000272View
2D structure for PGDB_C003354
IC50-=4.3nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A063345PGDB_C003354PGDB_AS000272View
2D structure for PGDB_C003335
IC50-=22nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A064935PGDB_C003335PGDB_AS000272View
2D structure for PGDB_C003333
IC50-=105nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A069374PGDB_C003333PGDB_AS000272View
2D structure for PGDB_C003355
IC50-=66nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A072819PGDB_C003355PGDB_AS000272View
2D structure for PGDB_C003348
IC50-=167nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A073329PGDB_C003348PGDB_AS000272View
2D structure for PGDB_C003342
IC50-=216nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A076592PGDB_C003342PGDB_AS000272View
2D structure for PGDB_C000058
IC50-=1.3nM-—GSPT1-SK-BR-3WO2025146129A1PGDB_A077717PGDB_C000058PGDB_AS000272View
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