Activity record

PGDB_A025679

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

degradation = 25-50 %

TargetGSPT1
Concentration0.1 uM
Assay / Readoutpercent_remaining / % Degradation
Assay IDPGDB_AS001685
PatentUS20200369679A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C004434
Compound IDPGDB_C004434
CompoundI-4
Source record IDPGDB_C004434
InChIKeyPAJIVQURKVNBMV-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001685
Assay family% Degradation
Assay systemcell_based
Readoutpercent_remaining
Concentration0.1 uM
Detection targetprotein_degradation
TargetGSPT1
E3Not specified

Source evidence

Patent IDUS20200369679A1
Compound location

I-4

I-4 enlarged structureI-4 location on patent page 120
Activity table
Page 185 · table single