Activity record

PGDB_A026001

Assay: biochemicalTarget: KRASQC: standardized
Activity overview

IC50 = 1-10 nM

TargetKRAS
Time1 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS001818
PatentWO2025214350A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011616
Compound IDPGDB_C011616
CompoundExample 65
Source record IDPGDB_C011616
InChIKeyLWWOZONPRHRKAA-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001818
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time1 h
TargetRAF1
E3Not specified

Source evidence

Patent IDWO2025214350A1
Compound location

Example 65

Example 65 enlarged structureExample 65 location on patent page 185
Activity table
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