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Compound
PGDB_C011616
10 activity records1 related patents
2D structure
CCn1c(-c2cc(C#CCN3CCN(C4COC4)CC3)cnc2C(C)OC)c2c3cc(ccc31)-c1csc(n1)CC(NC(=O)C1C(C)C1C)C(=O)N1NC(C(=O)OCC(C)(C)C2)C2CC1C2Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 1-10 | nM | - | — | - | - | AsPC-1 | WO2025214350A1 | PGDB_A024416 | PGDB_C011616 | PGDB_AS001410 | View |
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A024887 | PGDB_C011616 | PGDB_AS002054 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A026001 | PGDB_C011616 | PGDB_AS001818 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | AGS | WO2025214350A1 | PGDB_A026489 | PGDB_C011616 | PGDB_AS000218 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | NCI-H358 | WO2025214350A1 | PGDB_A029661 | PGDB_C011616 | PGDB_AS001442 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | SW620 | WO2025214350A1 | PGDB_A036435 | PGDB_C011616 | PGDB_AS001156 | View |
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A042216 | PGDB_C011616 | PGDB_AS000928 | View |
| IC50 | - | = | 1-10 | nM | - | — | KRAS | - | HPAC | WO2025214350A1 | PGDB_A045312 | PGDB_C011616 | PGDB_AS002124 | View |
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A048346 | PGDB_C011616 | PGDB_AS000791 | View |
| IC50 | - | = | 10-100 | nM | - | — | KRAS | - | - | WO2025214350A1 | PGDB_A056776 | PGDB_C011616 | PGDB_AS000307 | View |