Activity record

PGDB_A026459

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

degradation >= 80 %

TargetGSPT1
Concentration0.1 uM
Assay / Readoutpercent_remaining / % Degradation
Assay IDPGDB_AS001685
PatentUS20200369679A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C004435
Compound IDPGDB_C004435
CompoundI-5;I-5
Source record IDPGDB_C004435
InChIKeySKAIDPMCBUKTDS-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001685
Assay family% Degradation
Assay systemcell_based
Readoutpercent_remaining
Concentration0.1 uM
Detection targetprotein_degradation
TargetGSPT1
E3Not specified

Source evidence

Patent IDUS20200369679A1
Compound location

I-5;I-5

I-5;I-5 enlarged structureI-5;I-5 location on patent page 122
Activity table
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