Activity record

PGDB_A026467

Assay: viabilityTarget: GSPT1QC: manual_curated
Activity overview

IC50 = <= 0.5 nM

TargetGSPT1
Cell lineHEK293T
Time7 d
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS002143
PatentWO2025162410A1
QC statusmanual_curated
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020479
Compound IDPGDB_C020479
Compound5-2-8
Source record IDPGDB_C020479
InChIKeyUIQTVQIEQAAPPK-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002143
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time7 d
TargetGSPT1
E3Not specified
Cell lineHEK293T
OrganismHomo sapiens

Source evidence

Patent IDWO2025162410A1
Compound location

5-2-8

5-2-8 enlarged structure5-2-8 location on patent page 100
Activity table
Page 110 · table start