Activity record

PGDB_A029566

Assay: % DegradationTarget: CDK2QC: ambiguous
Activity overview

Dmax = 45 %

TargetCDK2
Cell lineHEK293
Concentration10 uM
Time18 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS001468
PatentWO2025043225
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007935
Compound IDPGDB_C007935
Compound4;4;4
Source record IDPGDB_C007935
InChIKeyNKZJXHXAUVLOSB-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001468
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Concentration10 uM
Treatment time18 h
TargetCDK2
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

4;4;4

4;4;4 enlarged structure4;4;4 location on patent page 21
Activity table
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