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Compound
PGDB_C007935
5 activity records1 related patents
2D structure
CC1CCc2nc(COC(=O)NCc3ccc4c(c3)C(=O)N(C3CCC(=O)NC3=O)C4)sc2C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dmax | - | = | 39 | % | 10 uM | 6 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A021055 | PGDB_C007935 | PGDB_AS002435 | View |
| Dmax | - | = | 45 | % | 10 uM | 18 h | CDK2 | - | HEK293 | WO2025043225 | PGDB_A029566 | PGDB_C007935 | PGDB_AS001468 | View |
| IC50 | - | = | 0.15 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A034508 | PGDB_C007935 | PGDB_AS002309 | View |
| IC50 | - | = | 0.16 | uM | - | — | CDK2 | - | HEK293 | WO2025043225 | PGDB_A035971 | PGDB_C007935 | PGDB_AS002528 | View |
| IC50 | - | = | 0.2 | uM | - | — | CRBN | CRBN | - | WO2025043225 | PGDB_A068177 | PGDB_C007935 | PGDB_AS001908 | View |