Activity record

PGDB_A029905

Assay: viabilityTarget: CDK12QC: ambiguous
Activity overview

IC50 = 8.9 nM

TargetCDK12
Cell lineA673
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS002202
PatentCN114929708B
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C006571
Compound IDPGDB_C006571
CompoundH-APPAMP-004
Source record IDPGDB_C006571
InChIKeyJRUVGDRUEWKQQJ-XLIONFOSSA-N

Assay context

Assay IDPGDB_AS002202
Assay familyviability
Assay systemcell_based
ReadoutIC50
TargetCDK12 | CCNK
E3Not specified
Cell lineA673

Source evidence

Patent IDCN114929708B
Compound location

H-APPAMP-004

H-APPAMP-004 enlarged structureH-APPAMP-004 location on patent page 37
Activity table
Page 197 · table single