Activity record

PGDB_A031544

Assay: % DegradationTarget: POLR2AQC: ambiguous
Activity overview

IC50 > 3 uM

TargetPOLR2A
Assay / ReadoutIC50 / % Degradation
Assay IDPGDB_AS000589
PatentWO2025110815A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010927
Compound IDPGDB_C010927
Compound24
Source record IDPGDB_C010927
InChIKeyZAMQVBPUZUUNBV-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000589
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
TargetPOLR2A
E3Not specified

Source evidence

Patent IDWO2025110815A1
Compound location

24

24 enlarged structure24 location on patent page 83
Activity table
Page 148 · table start
Page 149 · table middle
Page 150 · table end