Activity record

PGDB_A034508

Assay: % DegradationTarget: CDK2QC: ambiguous
Activity overview

IC50 = 0.15 uM

TargetCDK2
Cell lineHEK293
Time18 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS002309
PatentWO2025043225
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007935
Compound IDPGDB_C007935
Compound4;4;4
Source record IDPGDB_C007935
InChIKeyNKZJXHXAUVLOSB-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002309
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time18 h
TargetCDK2
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

4;4;4

4;4;4 enlarged structure4;4;4 location on patent page 21
Activity table
Page 525 · table start
Page 526 · table end