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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A036017

Assay: % DegradationQC: standardized

Activity overview

DC50 > 10000 nM

Cell line293T.114

TimeDC50 > 10000 nM | > 100 nM | DC50 < 100 nM

Assay / Readoutluminescence / DC50

Assay IDPGDB_AS001223

PatentWO2022081927A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C015421

Compound78

Source record IDPGDB_C026771

InChIKeyVGYLUWYHUSGMPW-HKBQPEDESA-N

Assay context

Assay IDPGDB_AS001223

Assay family% Degradation

Assay systemcell_based

ReadoutDC50

Technologyluminescence

Treatment timeDC50 > 10000 nM | > 100 nM | DC50 < 100 nM

TargetGSPT1

E3Not specified

Cell line293T.114

OrganismHomo sapiens

Source evidence

Patent IDWO2022081927A1

Compound location

78

78 enlarged structure

78 location on patent page 532

Activity table

Page 529 · table start

Page 530 · table middle

Page 531 · table middle

Page 532 · table middle

Page 533 · table middle

Page 534 · table middle

Page 535 · table middle

Page 536 · table middle

Page 537 · table middle

Page 538 · table middle

Page 539 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU