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Compound
PGDB_C015421
7 activity records2 related patents
2D structure
N#Cc1ccc(N2CCN(Cc3ccc(Cc4ccc5c6c(cccc46)C(=O)N5[C@H]4CCC(=O)NC4=O)cc3)CC2)c(F)c1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DC50 | - | < | 100 | nM | - | — | - | - | NCI-H929.11 | WO2022081927A1 | PGDB_A021519 | PGDB_C015421 | PGDB_AS000877 | View |
| Emax | - | < | 45 | % | - | DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | DC50 < 100 nM | - | - | NCI-H929.11 | WO2022081927A1 | PGDB_A025300 | PGDB_C015421 | PGDB_AS001790 | View |
| Emax | - | > | 60 | % | - | DC50 > 10000 nM | > 100 nM | DC50 < 100 nM | - | - | 293T.114 | WO2022081927A1 | PGDB_A027885 | PGDB_C015421 | PGDB_AS000287 | View |
| Emax | - | < | 45 | % | - | DC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | > 100 nM | - | - | KELLY.2 | WO2022081927A1 | PGDB_A033234 | PGDB_C015421 | PGDB_AS000499 | View |
| DC50 | - | > | 10000 | nM | - | — | - | - | 293T.114 | WO2022081927A1 | PGDB_A036017 | PGDB_C015421 | PGDB_AS001223 | View |
| IC50 | - | < | 1 | nM | - | — | - | - | NCI-H929 | EA048567B1 | PGDB_A067513 | PGDB_C015421 | PGDB_AS000893 | View |
| DC50 | - | < | 100 | nM | - | — | - | - | KELLY.2 | WO2022081927A1 | PGDB_A070620 | PGDB_C015421 | PGDB_AS001296 | View |