Activity record

PGDB_A036141

Assay: viabilityTarget: GSPT1QC: ambiguous
Activity overview

GI50 = 4.07 nM

TargetGSPT1
Cell lineSU-DHL-2
Time48 h
Assay / ReadoutGI50 / viability
Assay IDPGDB_AS000205
PatentWO2023237116A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002229
Compound IDPGDB_C002229
CompoundExample 16
Source record IDPGDB_C002229
InChIKeyPFANWFNVGAICOQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000205
Assay familyviability
Assay systemcell_based
ReadoutGI50
Treatment time48 h
Detection target% Cell viability
TargetGSPT1
E3Not specified
Cell lineSU-DHL-2

Source evidence

Patent IDWO2023237116A1
Compound location

Example 16

Example 16 enlarged structureExample 16 location on patent page 146
Activity table
Page 381 · table single