Activity record

PGDB_A036534

Assay: % DegradationTarget: CDK2QC: standardized
Activity overview

Dmax = 52 %

TargetCDK2
Cell lineHEK293
Concentration10 uM
Time6 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS002435
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007963
Compound IDPGDB_C007963
Compound32;32;32
Source record IDPGDB_C007963
InChIKeyOQQOMIUYKQULAS-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002435
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Concentration10 uM
Treatment time6 h
TargetCDK2
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

32;32;32

32;32;32 enlarged structure32;32;32 location on patent page 23
Activity table
Page 525 · table start
Page 526 · table end