Activity record

PGDB_A040319

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 < 1 uM

TargetCRBN
E3 ligaseCRBN
Assay / Readoutfluorescence / IC50
Assay IDPGDB_AS001252
PatentWO2022066835A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019545
Compound IDPGDB_C019545
Compound5;5;5
Source record IDPGDB_C001365
InChIKeyFURMQZYSFFTQLK-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001252
Assay familybinding
Assay systembiochemical
ReadoutIC50
Technologyfluorescence
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2022066835A1
Compound location

5;5;5

5;5;5 enlarged structure5;5;5 location on patent page 152
Activity table
Page 165 · table single