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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A040912

Assay: % DegradationTarget: VAV1QC: standardized

Activity overview

Dmax = 97 %

TargetVAV1

Cell lineJurkat

ConcentrationConcentration series: 1000 nM, 250 nM, 62.5 nM, 15.6 nM, 3.9 nM, 0.98 nM, 0.24 nM, 0 nM

Time24 h

Assay / ReadoutWestern_blot / Dmax

Assay IDPGDB_AS000206

PatentWO2026041143A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C009246

Compound6;化合物 6;化合物 6

Source record IDPGDB_C009246

InChIKeyYIBVZANKSZIAIX-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000206

Assay family% Degradation

Assay systemcell_based

ReadoutDmax

TechnologyWestern_blot

ConcentrationConcentration series: 1000 nM, 250 nM, 62.5 nM, 15.6 nM, 3.9 nM, 0.98 nM, 0.24 nM, 0 nM

Treatment time24 h

Detection targetprotein_degradation

TargetVAV1

E3Not specified

Cell lineJurkat

Source evidence

Patent IDWO2026041143A1

Compound location

6;化合物 6;化合物 6

6;化合物 6;化合物 6 enlarged structure

6;化合物 6;化合物 6 location on patent page 41

Activity table

Page 53 · table single

A patent-derived molecular glue bioactivity database with traceable evidence.

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0 countries/regions

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SIMM · NJU