PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

4 activity records

Assay family% Degradation

Systemcell_based

ReadoutDmax

TargetVAV1

E3Not specified

Cell lineJurkat

TechnologyWestern_blot

Detection targetprotein_degradation

Activity compounds and values

4 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
Dmax	-	=	98.1	%	Concentration series: 1000 nM, 250 nM, 62.5 nM, 15.6 nM, 3.9 nM, 0.98 nM, 0.24 nM, 0 nM	24 h	VAV1	-	Jurkat	WO2026041143A1	PGDB_A014016	PGDB_C009245	PGDB_AS000206	View
Dmax	-	=	97	%	Concentration series: 1000 nM, 250 nM, 62.5 nM, 15.6 nM, 3.9 nM, 0.98 nM, 0.24 nM, 0 nM	24 h	VAV1	-	Jurkat	WO2026041143A1	PGDB_A040912	PGDB_C009246	PGDB_AS000206	View
Dmax	-	=	96	%	Concentration series: 1000 nM, 250 nM, 62.5 nM, 15.6 nM, 3.9 nM, 0.98 nM, 0.24 nM, 0 nM	24 h	VAV1	-	Jurkat	WO2026041143A1	PGDB_A053339	PGDB_C009248	PGDB_AS000206	View
Dmax	-	=	97.7	%	Concentration series: 1000 nM, 250 nM, 62.5 nM, 15.6 nM, 3.9 nM, 0.98 nM, 0.24 nM, 0 nM	24 h	VAV1	-	Jurkat	WO2026041143A1	PGDB_A056571	PGDB_C009247	PGDB_AS000206	View

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