Activity record

PGDB_A041929

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 0.5-1 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000323
PatentCN120548310A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000760
Compound IDPGDB_C000760
CompoundGT-04379
Source record IDPGDB_C000760
InChIKeyPHPAEVAXSBDUED-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000323
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDCN120548310A
Compound location

GT-04379

GT-04379 enlarged structureGT-04379 location on patent page 23
Activity table
Page 146 · table single