Activity record

PGDB_A043170

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 36.9 nM

TargetGSPT1
Cell lineHNT-34
Time72 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS000001
PatentWO2023078410A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005337
Compound IDPGDB_C005337
Compound5-10;5-10;5-10
Source record IDPGDB_C005337
InChIKeyFGTRILYTYCCJMG-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000001
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineHNT-34

Source evidence

Patent IDWO2023078410A1
Compound location

5-10;5-10;5-10

5-10;5-10;5-10 enlarged structure5-10;5-10;5-10 location on patent page 9
Activity table
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