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Compound
PGDB_C005337
4 activity records1 related patents
2D structure
O=C1CCC(N2Cc3cc(CNC(=O)C(CNC(=O)Oc4ccccc4)c4ccccc4)ccc3C2=O)C(=O)N1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 37.7 | nM | - | — | GSPT1 | - | HL-60 | WO2023078410A1 | PGDB_A031835 | PGDB_C005337 | PGDB_AS002047 | View |
| IC50 | - | = | 36.9 | nM | - | — | GSPT1 | - | HNT-34 | WO2023078410A1 | PGDB_A043170 | PGDB_C005337 | PGDB_AS000001 | View |
| % Degradation | - | = | 73 | % | 100 nM | 24 h | GSPT1 | - | JeKo-1 | WO2023078410A1 | PGDB_A045406 | PGDB_C005337 | PGDB_AS002119 | View |
| % Degradation | - | = | 90 | % | 10 uM | 24 h | GSPT1 | - | JeKo-1 | WO2023078410A1 | PGDB_A054710 | PGDB_C005337 | PGDB_AS000305 | View |