Activity record

PGDB_A043590

Assay: viabilityTarget: KRASQC: standardized
Activity overview

IC50 = 0.3578 nM

TargetKRAS
Cell lineAsPC-1
Time5 d
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS001203
PatentCN121181579A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024673
Compound IDPGDB_C024673
Compound实施例130
Source record IDPGDB_C024673
InChIKeyAWODYYNDRXVFPH-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001203
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time5 d
Detection targetcell_proliferation
TargetKRAS
E3Not specified
Cell lineAsPC-1
OrganismHomo sapiens

Source evidence

Patent IDCN121181579A
Compound location

实施例130

实施例130 enlarged structure实施例130 location on patent page 129
Activity table
Page 146 · table single