Activity record

PGDB_A044235

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 1.5-1.9 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS002101
PatentWO2024245444A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019997
Compound IDPGDB_C019997
CompoundGT-06450
Source record IDPGDB_C019997
InChIKeyDCLOSGUKKZFNTI-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002101
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2024245444A1
Compound location

GT-06450

GT-06450 enlarged structureGT-06450 location on patent page 58
Activity table
Page 260 · table single